Hudbu jak k seriálu, tak k filmu složil skladatel Angelo Badalamenti, texty písní napsal David Lynch. Ve zpívaných skladbách zní hlas Julee Cruise, která si sama v Twin Peaks zahrála v roli barové zpěvačky. Sama zpěvačka vydala dvě desky, hudbu opět dělal Badalamenti, texty napsal Lynch.

1. Twin Peaks Theme (Instrumental)
2. Laura Palmer’s Theme (Instrumental)
3. Audrey’s Dance (Instrumental)
4. The Nightingale (Vocal by Julee Cruise)^*
5. Freshly Squeezed (Instrumental)
6. The Bookhouse Boys (Instrumental)
7. Into the Night (Vocal by Julee Cruise)^*
8. Night Life In Twin Peaks (Instrumental)
9. Dance Of the Dream Man (Instrumental)
10. Love Theme From Twin Peaks (Instrumental)
11. Falling (Vocal by Julee Cruise)^*

1. Theme from Twin Peaks - Fire Walk With Me
2. The Pine Float
3. Sycamore Trees Vocal by Jimmy Scott
4. Don't Do Anything (I Wouldn't Do)
5. A Real Indication Thought Gang/Vocal by Angelo Badalamenti
6. Questions in a World of Blue^*
7. The Pink Room
8. The Black Dog Runs at Night Thought Gang/Vocal by Angelo Badalamenti
9. Best Friends
10. Moving Throught Time
11. Montage from Twin Peaks Girl Talk/Birds in Hell/Laura Palmer's Theme/Falling
12. The Voice of Love^*